Miscellaneous. Atypical lymphocytes resembling these of Infectious mononudeosis though in smaller nuirbeis

lymphocytosis with atypical lymphocytes Lymphadenopathy commonty involves anterior And posterior cervical nodes Masanetric. madiasllnal, axillary and Inguinal lymphnodes may also become enlarged Nodes may be mobile, discrete and accasioinally tender Diagnoss established by demonstration of antibodies and occasionally by lymph node biopsy 8 Cal-scratch disease- Papular or puetular lestore develop soon after cat scratch or bite. Lymphadenopathy develops over fallowing two weeks Usually only a single node draining the site of tha lesion is aflected, hacoming tender and cccasionally undergoing suppuration. The lymphadenopathy usually regresses within a few weeks, but persistent or recurrent node enlargement may occur Mora pronounced, systerrc farms of Ihe deease are in the from of splenomegaly in children and meningoencephalitis in adults. The histology of cat-scratch disease adenopathy Is generally Indistlnguishable from that of fuberculose or sarcoidosis. B DISORDERS WITH SIMILAR BLOOD PICTURE 1 Acute lymphocyte leukemia - Immature lymphocytes, high total count, anaemia and thrombocytopenia and negative Paul-Bunnell test 2. Acute infectious lymphocytosis - Mature lymphocytea and negative Paul-Bunnell test. 3. Miscellaneous. Atypical lymphocytes resembling these of Infectious mononudeosis though in smaller nuirbeis appear in viral hepatitis, serum sickness. Hodgkin's diseasa, rubella, brucellosis, toxoplasma, cytomegaovirus or adenovirus infection. Complicathons • 1 Aulolrrmune hemolytic anemia - rare Spontaneous resolution Rarely thrornbocytopenia with bleadng Splenic rupture Z. Neurological - Encephalitis